Il-6 Receptor Antagonist

NMDA receptor antagonist 6
HY-155049 Get quote Ask for price
Description: NMDA receptor antagonist 6 (compound 13b) is an antagonist of NMDA receptor, targeting to the glycine binding site. NMDA receptor antagonist 6 shows cytoneuroprotective potency, and protects PC12 cells against NMDA-induced injury and cell apoptosis[1].

Human IgG antibody Laboratories manufactures the il-6 receptor antagonist reagents distributed by Genprice. The Il-6 Receptor Antagonist reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact il 6 elisa. Other Il-6 products are available in stock. Specificity: Il-6 Category: Receptor Group: Antagonist

RXR antagonist 6
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Description: RXR antagonist 6 (Compound 33) is a highly selective RXR agonist, with EC50s of 9 nM, 18 nM, and 11 nM for RXRα, RXRβ, and RXRγ, respectively. RXR antagonist 6 binds to RXR with high affinity (Kd = 0.03 μM)[1].

AHR antagonist 6
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Description: AHR antagonist 6 (Compound 44) is an aryl hydrocarbon receptor (AHR) antagonist used in cancer research[1].

CXCR2 antagonist 6
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Description: CXCR2 antagonist 6 (compound 35c) is a potent CXCR2 antagonist. CXCR2 antagonist 6 shows potent CXCR2 binding affinity (IC50=0.044 µM) and calcium mobilization (IC50=0.66 µM)[ 1].

MrgprX2 antagonist-6
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Description: MrgprX2 antagonist-6 (compound 9) is an anti-allergic agent. MrgprX2 antagonist-6 shows excellent anti-allergy effects and can inhibit mast cell degranulation[1].

CXCR4 antagonist 6
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Description: CXCR4 antagonist 6 (compound 46) is a potent CXCR4 antagonist with an IC50 value of 79 nM. CXCR4 antagonist 6 inhibits CXCL12 induced cytosolic calcium flux (IC50 = 0.25 nM). CXCR4 antagonist 6 significantly mitigates CXCL12/CXCR4 mediated cell migration. CXCR4 antagonist 6 exhibits marked efficacy in a cancer metastasis model in mice[1].

A1AR antagonist 6
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Description: A1AR antagonist 6 (compound 15) is a potent and selective A1AR (A1 adenosine receptor) antagonist, with a pIC50 of 6.38 and a pKi of 7.13[1].

CCR1 antagonist 6
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Description: CCR1 antagonist 6

Antagonist information

Anti-Mouse IL-1 receptor antagonist Antibody
103-M413 100 µg
EUR 399
Description: IL-1 receptor antagonist (IL-1ra) was originally isolated from the urine of patients with monocytic leukemia and has also been purified from adherent monocytes. The protein shows 26% amino acid homology to IL-1 beta and 19% homology to IL-1 alpha. It will compete with either factor for receptor binding, but does not interact with either one. Human IL-1ra will bind to both types of IL-1 receptor (I and II) on human cells. In mouse, IL-1RII does not bind IL-1ra.

Anti-Human IL-1 receptor antagonist Antibody
101-M501 100 µg
EUR 399
Description: IL-1 receptor antagonist (IL-1ra) was originally isolated from the urine of patients with monocytic leukemia and has also been purified from adherent monocytes. The protein shows 26% amino acid homology to IL-1 beta and 19% homology to IL-1 alpha. It will compete with either factor for receptor binding, but does not interact with either one. Human IL-1ra will bind to both types of IL-1 receptor (I and II) on human cells. In mouse, IL-1RII does not bind IL-1ra.

Anti-Human IL-1 Receptor Antagonist Antibody
GWB-268D1A 1 mg Ask for price

IL-1RA, Interleukin-1 receptor antagonist, human
RC212-12C 20ug
EUR 125.26

Interleukin 1 Receptor Antagonist (IL-1RA) Antibody
20-abx225243
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VIP Receptor Antagonist
064-22 200 μg
EUR 114.48

[D-Lys3]-GHRP-6 / Ghrelin Receptor Antagonist
031-22 500 μg
EUR 114.48

IL-1 Receptor Antagonist Protein polyclonal antibody
BZ16698 50ul
EUR 358
Description: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

IL-1 Receptor Antagonist Protein monoclonal antibody
MB11101 50ul
EUR 398
Description: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

σ1 Receptor antagonist-1
HY-10815 1 mg
EUR 619.06
Description: σ1 Receptor antagonist-1 is a highly potent and selective sigma 1 receptor antagonist (pKi=10.28). σ1 Receptor antagonist-1 inhibits cell growth, arrests cell cycle at G0/G1 phase and induces apoptosis of MCF-7/ADR cells[1].

σ1 Receptor antagonist-1
T9244-10mg 10mg Ask for price
Description: σ1 Receptor antagonist-1

σ1 Receptor antagonist-1
T9244-1g 1g Ask for price
Description: σ1 Receptor antagonist-1

σ1 Receptor antagonist-1
T9244-1mg 1mg Ask for price
Description: σ1 Receptor antagonist-1

σ1 Receptor antagonist-1
T9244-50mg 50mg Ask for price
Description: σ1 Receptor antagonist-1

σ1 Receptor antagonist-1
T9244-5mg 5mg Ask for price
Description: σ1 Receptor antagonist-1

IL1RA/IL-1 Receptor Antagonist Protein Rabbit pAb
E2381345 100ul
EUR 225
Description: Available in various conjugation types.

EP2 receptor antagonist-2
HY-153129 10 mg
EUR 735.94
Description: EP2 receptor antagonist-2 (CID891729) is an antagonist of EP2 receptor. EP2 receptor antagonist-2 inhibits the EP2 receptor activation induced by PGE2. EP2 receptor antagonist-2 also suppresses lactate dehydrogenase (LDH) release induced by N-methyl-D-aspartate (NMDA)[1].